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If a significant loss of drug product is observed or suspected because of vomiting, a second full dose of Lariam should be administered to patients who vomit less than 30 minutes after receiving the drug. An information wallet card is also supplied to patients when Lariam is dispensed. Women of childbearing potential should also be advised to practice contraception during malaria prophylaxis with Lariam and for up to 3 months thereafter. The safety and effectiveness of Lariam for the treatment of malaria in pediatric patients below the age of 6 months have not been established. Lariam should be used with caution in patients with a previous history of depression. Thus, concomitant administration of Lariam and substrates of the CYP 450 enzyme system is not expected to result in a drug interaction.
lariam information at Drugs.com
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